Site-specific Allylic C-H Bond Functionalization with a Copper-Bound N-Centred Radical

A copper-catalyzed site- and enantio-selective allylic C–H cyanation of complex alkenes was developed, where an unprecedented Cu(II)-bound N-centered radical is the key to achieve the precise site-specific HAT. This method is shown to be effective with a diverse collection of alkene-containing molecules, including sterically demanding structures and complex natural products and pharmaceuticals. This result is published in Nature. Congratulations Jiayuan Li. Read More

Congratulations to Lianqian Wu(吴联谦) and Xiang Li(李响) on obtaining their PhD degree.

Welcome Dr. Weigang Fan from Université de Lyon, INSA Lyon (France) to join our group as a Postdoc.